Topic
Biomarkers
Lab tracking, ApoB, HbA1c, inflammatory markers, and lab trends.
Casey MillsDoes the Erythritol in Your Sugar-Free Snacks Raise Your Blood-Clot Risk?
A 2024 Cleveland Clinic trial found that 30 grams of erythritol, the sugar alcohol in most keto sweeteners and zero-sugar sodas, made platelets clot-prone in every volunteer, while plain glucose did nothing.
Evelyn CrossDoes Exercise Actually Raise Klotho, the Longevity Protein Scientists Are Racing to Inject?
Scientists are fast-tracking injectable klotho after a single shot sharpened memory in aged monkeys, but your own muscles already make this longevity protein, and twelve weeks of training reliably raises it.
Atlas MercerDo Continuous Glucose Monitors Overestimate Your Blood Sugar Spikes?
A University of Bath crossover trial found a FreeStyle Libre 2 rated a smoothie medium-to-high GI while a finger-prick test rated it low, and the sensor overestimated time above range severalfold.
Casey MillsDoes Eating Two Kiwifruit a Day Actually Fix Constipation Better Than Prunes?
If you have spent any time on the internet looking for a food that keeps things moving, you have met the prune. It works. But prunes are sweet, sorbitol-heavy, and a lot of people find two servings a day rough on the…
Evelyn CrossCan a 5-Day Fasting-Mimicking Diet Actually Lower Your Biological Age?
Most of what gets sold as "resetting your metabolism" is marketing. But the fasting-mimicking diet (FMD) developed by Valter Longo's group at USC is one of the few caloric-restriction protocols with an actual human tr…
Casey MillsDoes Eating Your Protein and Vegetables in a Fixed Order at Every Meal Actually Do Anything Long-Term?
You've probably heard the "veggies first, protein next, carbs last" advice by now. The short-term glucose data behind it is real: in people with type 2 diabetes, eating vegetables and protein before carbohydrate blunt…
Evelyn CrossDoes Your Grip Strength Actually Predict How Long You'll Live?
Here is a longevity biomarker that costs almost nothing to measure and beats most of the fancy panels I get asked about: how hard you can squeeze a dynamometer. In a prospective study of nearly 140,000 adults across 1…
Atlas MercerHow Long After a High-Fat Meal Does Your Blood Vessel Function Drop?
A single high-fat meal degrades endothelial function within hours. This is not a diet debate; it is a measurable, transient vascular event, and the timing is precise enough to build a protocol around. The standard mea…
Casey MillsDoes Adding Vinegar to a Meal Actually Lower Your Blood Sugar Spike?
Vinegar has been folk medicine for centuries, but the modern version of the claim is specific: a tablespoon or two of vinegar with a carb-heavy meal blunts the glucose response. The interesting part is that it mostly…
Atlas MercerHow Long Does One Night of Poor Sleep Impair Your Insulin Sensitivity?
The system fails faster than most people assume. In a controlled crossover trial, healthy young men subjected to a single night of total sleep deprivation showed a measurable drop in whole-body insulin sensitivity the…
Max KlineDoes Eating Earlier in the Day Actually Help You Lose More Fat Than Eating the Same Calories Later?
Here is a question I get from people who refuse to count a single extra calorie but still want a free lever: does it matter *when* I eat if the total stays the same? The honest answer used to be "probably not, energy…
Casey MillsDoes Eating Protein Before Carbs Actually Lower Your Blood Sugar Spike?
Order of operations turns out to matter at the dinner table, and not in a way I expected when I first read the data. If you eat your vegetables and protein first and save the rice or bread for last, your post-meal blo…
Evelyn CrossThe Asymmetric Upside of Taurine in the Longevity Toolkit
When we discuss molecular interventions for aging, the conversation usually defaults to rapamycin, senolytics, or NAD precursors. But one of the most compelling additions to the longevity landscape recently involves a…
