Topic
Longevity
Healthspan, biological aging, and decisions whose payoff is decades.
Atlas MercerDoes Wearing a Weighted Vest While Losing Weight Actually Protect Your Bones?
A 12-month randomized trial put weighted vests on older adults through a 10 percent weight-loss phase, and hip bone density fell 1.2 to 1.9 percent in every arm, vest or not.
Evelyn CrossDoes Exercise Actually Raise Klotho, the Longevity Protein Scientists Are Racing to Inject?
Scientists are fast-tracking injectable klotho after a single shot sharpened memory in aged monkeys, but your own muscles already make this longevity protein, and twelve weeks of training reliably raises it.
Evelyn CrossDoes Rapamycin Actually Slow Aging in Humans? What the First Year-Long Trial Found
Rapamycin reliably extends lifespan in mice, but the first year-long randomized human trial found it did nothing to its main aging target, visceral fat.
Evelyn CrossCan a 5-Day Fasting-Mimicking Diet Actually Lower Your Biological Age?
Most of what gets sold as "resetting your metabolism" is marketing. But the fasting-mimicking diet (FMD) developed by Valter Longo's group at USC is one of the few caloric-restriction protocols with an actual human tr…
Max KlineDoes Taking Your Omega-3 Fish Oil Actually Slow Down How Fast Your Cells Age?
Telomere length is the closest thing we have to a cellular odometer, and most interventions that claim to move it are noise dressed up as signal. So when a randomized controlled trial actually shows a shift, I pay att…
Evelyn CrossDoes Your Grip Strength Actually Predict How Long You'll Live?
Here is a longevity biomarker that costs almost nothing to measure and beats most of the fancy panels I get asked about: how hard you can squeeze a dynamometer. In a prospective study of nearly 140,000 adults across 1…
Atlas MercerHow Long After a High-Fat Meal Does Your Blood Vessel Function Drop?
A single high-fat meal degrades endothelial function within hours. This is not a diet debate; it is a measurable, transient vascular event, and the timing is precise enough to build a protocol around. The standard mea…
Casey MillsDoes Eating Kimchi and Yogurt Actually Change Your Gut Bacteria More Than a High-Fiber Diet?
If you've ever wondered whether the more effective move is piling on the sauerkraut or piling on the lentils, a Stanford trial from a few years back gave a surprisingly clear answer, and it's not the one most fiber ev…
Evelyn CrossThe Asymmetric Upside of Taurine in the Longevity Toolkit
When we discuss molecular interventions for aging, the conversation usually defaults to rapamycin, senolytics, or NAD precursors. But one of the most compelling additions to the longevity landscape recently involves a…
Atlas MercerThe Superiority of Sleep Regularity Over Duration
The default assumption in human recovery is that sleep volume dictates physiological repair. When a deficit occurs, the standard behavioral response is to extend sleep duration on subsequent days to catch up. This is…
